I've been using Cakewalk for years and more recently Pro Tools on both my desktop (home-assembled) and an older gaming laptop I use for a portable recording DAW. I've had no issues with Windows 10 (was able to record a set of drums with 12 mics on the laptop with no issues). I know the quality of the drivers of your interface can be a big factor though... I use an RME Fireface UFX that I've had for six or seven years and their drivers are rock solid and are still supported for this device. Our guitarist has a Focusrite 18i20 and it also works wonderfully. I had a MOTU 828mkII before the RME; The hardware was outstanding, but their Windows drivers weren't very good at the time.