Highway One is basically a MIM Standard, except the tone circuit is different and the pickups are different. Not sure what kind of finish they have on the back of the neck, but I can't stand the greasebucket tone circuit on a P bass, and if someone gave me a Highway One I would replace that right away. Like the MIM standards, they have the regular open back 70's style tuners, and...maybe a Bad Ass II bridge? Not sure. I also hate those bridges. So that's my two bits about that.
The American Standard has rolled fretboard edges, lightweight tuners, very decent pickups (I still have the '62's in mine, but the SPB-1 in another P bass), high mass string-through bridge, CTS pots, and a satin finish on the back of the neck. In my own personal opinion, there is *no better* P neck, unless maybe the Deluxe/Elite/Ultra series. It is very comfy to play for 4 hours, almost a joy for my left hand when I finish the 4th set of the night, versus pretty much anything else. I've owned several, a 1996, 2006, 2008, 2010, 2016, and my current 2014 American P, not to mention several Jazzes, Mexi's, Squiers, and non-Fenders. I am also very impressed with the 2017-current American Pro neck, which is slightly different (63 neck profile and tall frets), but I've only ever played those in stores so can't attest to how comfortable they are in a gig.
Like I said, in my experience the 2012-2016/2017 American Standards are the best Fender has ever made, close second by the 2008-2011 ones which just had a different pickup. The professionals I can't speak to, but I like what I've seen. I'm sure you'll be happy with the CS62 pickup, but if you ever experiment, I can't recommend the SPB-1 enough.