Yea I remembered reading somewhere that running the main wide open would eat power tubes faster so I shy'd away, but no more. I'm down with replacing power tubes more often if I get a tone like that.
Not true. The master is most often a preamp attenuator. When the master is turned up, it is basically a non master amp with the volume control setting the overall level. The power tubes wear down based on how hard you push them. Play with the volume level cranked and you wear down the power tubes faster.
BUT, if you crank the gain and turn down the master, you will wear down the preamp tubes faster.
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I may try my V4B on top of my GB NX2-212T cab to see if I can handle that look in person.