Funny thing for me is over the years, I was always a 10's guy, and really disliked 12's, except for my B12 Portaflex. I also have the Epifani UL2x12 and I never use it, too scooped for me. The ML112 is the first 12 I ever liked, let me rephrase that, LOVE!
I don't miss my 10's at all... And I had them all over the years.
Well except maybe for my mesa boogie 4x10 roadready cab circa '92. That was one killer cab, but it killed your back too!
I think you will see two things happen (already happening) in the bass cabinet category:
1) You will see fewer and fewer multi-10 cabs. Given the improvements in speaker design, most high end 112's can EASILY perform at the level of an older 210 box, in a smaller size and less cost (1 driver versus 2). The cost advantage is even bigger when the cabs are neo. I believe, for example, the Eminence 3010LF is about the same price as the 12 and 15 variants.
2) You will hear fewer bassists talk about 'the sound of 10's' versus 'the sound of 12's' versus the 'sound of 15's'. Given the improvement in design over the last 10 years, it really is more a matter of scaling and volume than frequency range.
A 112 (for those who don't need a ton of volume) and a 212 ( or 2 x 112) for those that do seems to be the sweet spot these days regarding volume, size, overall performance, weight, and cost.

