After having played with it for some hours at home and bringing it to practice today, I must say I am impressed! I don't miss the Quad Cortex at all, as I can fit the Anagram in my bass bag. Compared to the QC, I find the interface of the Anagram much easier to use and it's a lot quicker to dial in a good bass tone. It sounds VERY good!
I really like the form factor and it's so easy to manage the change between preset/snapshot/stomp mode and assigning everything to what I need. The only niggle I have with the UI on the pedal is that popup eeevery time i want to copy a preset. It slows down the workflow in a very annoying way! A "dont show this again" button on it would be very welcome.
It is nice that the unit is bass-focused so I don't have to scroll through endless guitar things, but the NAM-capability makes it surprisingly good for playing guitar through as well.
The one real negative I have is the Darkglass software on PC/Mac. It's clunky and unintuitive and could need some work. Thankfully the ease of use on the pedal itself makes up for it for me, as I really only have to use the software to import NAM and IR profiles.
Switching over from the QC was a good decision, I think. I really like the Anagram so far.