Just thinking out loud here but, I'm having trouble seeing how the string has a brighter tone from a synthetic nut, than a steel fret. (I'm not a physics guy.

And after years of brass nuts I found it... interesting, that Dingwall's are synthetic)
I've heard "teachers" on you tube say "never play an open string". But of course that makes me go right out and play open strings. LOL It's the open B string that sold me on Dingwalls in the first place.
Like @BurningSkies said, it's preference. I also play with a pick 2/3, to 3/4 of the time.

But hey, that's me. I still like my RH750 too so...