Yes. This is an important "note".
Most bolt ons are just screwed in, which is a much lousier way to secure a neck than glue... now if they really were bolted, that would be very strong. To add insult to injury... After losing a strap button in 1992, I got into the silly habit of removing the strap button screws of all new guitars, and then reinstalling them with crazy glue on the threads.
As the years went on and I started installing strap locks, machine heads, bridges, pups, and different PG's on ALL of my new basses, I began using the crazy glue technique on all of the screws. Guess what I found?
Better than 35% of the screws on all of my USA Fenders and G&Ls were stripped from the factory. So, my trick works very well, but the glue is better than the screw...
I too have always been scared of set necks and I try to avoid them, but I'm also smart enough to know that I'm basing it on foolish OCD nonsense. If Slash, ACE, and Angus are using them, then I suspect you can too.