Regarding multieffects, they can definitely be used to get unexpected places... but require a bit of thought at times. I think that's why something which is weird out of the box, and which just has to be plugged in and used as is, has so much appeal.
I do love watching vids for things like the Line 6 M series, the Zoom G3/B3, as well as the EHX Effectology series, to see some of the more extreme uses to which they get put. Taking those ideas, and applying them to what I have, has gotten me a lot of places which might at first glance seem impossible with what I have on the board at the moment.