Can do. After selecting the Octave Up, set the level and processor pan lets you send it either 1, 2 or blend that, then the Destination lets you route signal to the next group of effects, the distortion+filter, filter only or to the direct output. For Octave up sounds I find it better to either just filter or direct output unless you want things extra crunchy. You can route it to Dist+filter and switch off the distortion if you prefer that sound, it does make a difference.
The Spectrum offers so many choices and it takes a while of reading, playing with the device until you grasp all the possibilities. The learning curve is steep but well worth the process.