Gauges make a pretty big difference. With the exception of my 2015 bird* (jury is still out on the best string for it) I find lighter gauges to be more articulate, cleaner and clearer sounding, much easier to bend and noticeably easier and frequently faster to play on the left or fretting hand. Conversely, I find heavy gauges to generally have a more authoritative sound, more heft, maybe more punch, less definition, longer decay and easier to play with the right hand. YMMVI have spent my time experimenting on different types (brand & construction) of strings figuring out what strings work on each bass (each bass seems to demand it's own particular strings). I haven't spent time experimenting with gauges but my teacher has encouraged me to start that experiment.
*i suspect, possibly because of the insanely strong pup magnets, in many areas the 2015 acts opposite of what I would normally expect from a light gauge string. However, I haven't been able to confirm that theory yet with a heavy gauge.


