Well, my wife has secondary progressive Multiple Sclerosis. For those that don't fully understand what that is, it's an incurable degenerative neurological disease that ultimately destroys the function of the central nervous system. In time, depending on the completely random nature of the disease progression, it may well leave her being unable to speak coherently, she may have to be tube fed because her ability to swallow may be totally impaired, she may have to be catheterised and have a colostomy to deal with dual incontinence, and she may lose the use of her legs and arms, may lose her sight or just about anything that is a function of the central nervous sytem...which is just about everything..
She is already reduced to being in a wheelchair full time, needs to have her food cut up for her because she can't use her hands properly and has some speech and cognitive issues that are typical of MS. The secondary progressive stage of the illness means that she no longer has periods of remission and, basically, it's all downhill from here - and some of the other symptoms described above are already starting to manifest themselves.
Outwardly, people with advanced stages of MS will look pretty much like Professor Stephen Hawking. He has Motor Neurone disease, which is a completely different thing, but the outward effects look pretty much the same...except that MS also impairs cognitive function.
We are both in our mid 50's. I work as a programme manager for a multinational, before my wife was diagnised and had to give up work because of her condition she was a paliative care nurse helping people with terminal conditions (including MS) to die with dignity. WE are not stoners.
And yet, canabinoids are reputedly very good at alleviating the constant neurological pain, cramps and muscle spasms that MS engenders, so we tried it a year or rwo ago on her birthday.
My wife has never smoked cigarettes and found smoking weed very difficult. I dabbled with Marijuana a couple of times in student days but left it alone for 30 plus years, so it wasn't easy....I couldn't even remember how to skin up properly.
Eventually, after a lot of inept floundering, we both managed to get moderately stoned and enjoyed one of the first evenings in years where we were both able to giggle like lunatics - just some brief respite from dealing with the relentless daily grind of dealing with a progressive, crippling deisease
That seems pretty positive to me.
We won't be making a habit of it, and haven't repeated the experience but it was fun while it lasted.