So many songs are in E, especially rock stuff. I've had it happen where I couldn't play that high E when i wanted to a couple of times. But I never worried about a note above that E. Maybe it's me personally but I think atleast few others would agree.
I don't get it. A Fender style 20 fret bass has every note exactly three times, no more, no less.
You want at least 21 - which gives you every note exactly three times... except E... you get 4 of those. Why should E be more special than the other 11 notes?