The two cabs would be 2.6 ohm wired together so youd need to use the 2 ohm setting on the titan. I think itd be ok but probably not louder than the 610 on the 4/8 setting.
I would strongly recommend ditching the sansamp and dialing in your sound with the titan EQ.
I would strongly recommend ditching the sansamp and dialing in your sound with the titan EQ.