I typically run the neck pickup parallel, bridge in series. That fattens up the bridge sound a bit and makes for a good volume balance between the two pickups. Since I don't use the 50/50 position much and tend not to like a very scooped tone, it works for me. But if I want a more "classic" Smith slap tone, easy to flick the switch.
Having worked through my initial setup and getting acclimated, I'm reminded of the reasons I like Smith basses. The tone is on the compressed/focused side which helps it cut, and I can just fiddle with the blend knob and get a bunch of tones I like.
6-string goodness
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