Ken, how often do you use your AE410? Do you find that you use your smaller cabs more often? Curious!
80%+ of my gigs. It is a relatively small 410, and with the castors, it is a great 'one trip cab' with one of my small heads and stand sitting on top and my bass on my back.(I most often use my RH450 with the AE410 and the Sadowsky now, although I like it with the Markbass F1 a lot too if you really want to grind and punch). It also is a cab that sounds fantastic at low volumes, due to its strong mid presence.
I have a hard time actually playing out of anything else at this point (although I still play my 410UL/F500 as my road rig... it stays in a remote location). The AE410 has a strong voice, and is kind of the opposite of the 410UL (which I know you are familiar with).... it is tight in the lows where the 410UL is big, it is punchy in the low mids, where the 410UL is a bit polite, it is very aggressive and grindy in the upper mids, where the 410UL is very smooth, and it is more 'lower treble aggressive' than the upper treble, airy 'click' of the 410UL... very, very different.
However, in a mix, it is just a HAMMER! It can get very burpy when digging in, and most importantly to me, the upper mid and treble are voiced to not get lost in the mix, which I hear happen SO often with many players' live tones... all low end, little articulation, and maybe just a little click up top in the treble.
I'm not a big fan of the HS410... nice sounding, much smoother than the AE410, and I guess if I was more into an old school tone.. more low mid push, more polite upper mids and treble, it would be great (it kind of sits between the AE410 and NV610 tonewise to my ear). However, the AE410 is just perfect for my tone goals, which you can hear on my Youtube clips. I need to hear those windings on the B string in a mix, and the AE410 totally will get you there. Of course, that kind of bright, aggressive articulation can be a bit much for some, so again, pure IMO there... the AE has a strong, punchy, forward voice that just speaks to me personally.
To oversimplify, I've described it many times this way:
AE410.... 'Flea'
410UL.....'Marcus'
HS410.... Joe Osborne'
Gross oversimplification... but a reasonable overview of the voicing of these popular 410's.