Do these cabs work well with low power amps. Like 250-300 watts?
Yup - they are very efficient for cabs that can handle lows - so they will work as good or better as anything else you might be familiar with [that can handle lows]. I use a 400+ with a 15/6 occasionally and it works fine [right up to where the Mesa runs out of gas and won't play clean anymore].
But with only 250/300 watts you are leaving a lot of cab on the table [un-utilized]. A 15/6 is excursion limited to about 750 watts so assuming a bit of cushion for headroom you could bring over 1k watts @ 8 ohms before you could be accused of "over amping" the cab - you might however be accurately accused of burying the band if you play the volume game.
