There are very few cabinets/ amps that don't have their speaker outputs/ daisy chains wired in parallel. The only one I've ever owned was a 70s Music Man HD-130 amp that had series-connected speaker outputs on the back of the amp. Super uncommon though!
If your cabs were connected in series, you'd only be running 16 ohms, so you would definitely notice a lack of headroom with that combo.
If your cabs were connected in series, you'd only be running 16 ohms, so you would definitely notice a lack of headroom with that combo.