Considering that pretty much all pedal boards filled with "traditional" pedals are generally wired right to left, I find the Left to Right signal flow view on the HX to be unusual. Not a big deal now that I know what's what, but perhaps giving the option to switch the view or at least putting some sort of indicator on that screen would be helpful. Oh well, now I know!
Surprisingly, for that particular preset when I realized my error, reordering didn't do a ton different to the sound. Biggest difference was having the Obsidian moved to last and my comp block moved to first. But even that was minimal change, sound-wise. The chorus tone I dialed with have to be adjusted. Probably the dirt sound I had arranged. But nothing I wasn't able to work with on the fly.
Figured it cause i was trying to assign expression pedal to the level on the comp block to feed a delay with long and full repeats. Would turn the expression down and the whole rest of the signal would go down too. Was driving me nuts for a bit!