My answer is going to be a bit different, but speaking from experience: yes. absolutely.
As others have said, it depends on how much the other musicians, especially the drummer have control, but I played 3 hours of hard bop in a bar with 2 horns, piano, and a bebop drummer once. There was a miscommunication on the amp. I powered through, it sounded great, but I was sore after. I had a residency years ago with baby grand piano and the world's most tasteful drummer and it was awesome playing without an amp.
BUT: the technique of the bassist is key. A lot of volume and projection comes from the technique of both hands and not everyone can do it. More to the point, someone coming from BG and bringing their approach with them could definitely not do it. There are really good doublebassist who probably couldn't and definitely wouldn't want to do it, because their playing style is softer touch and more amp dependent (a valid choice).
The other MAJOR factor that keeps me from leaving my amp home, even when I think I might be able to, is the room acoustics. Big vs Small is definitely a thing, but bass is loud in some rooms and quite in others. I've had the acoustic sound dramatically change first set to second, because there were more bodies in there to soak up the sound. Speculating here, but probably winter clothes vs summer clothes of the patrons could be a factor. The room is the big variable that you don't control.